Cell BiologybioRxivPreprint
TDP-43 oligomerization and RNA binding are codependent but their loss elicits distinct pathologies
M. Perez-Berlanga, V. I. Wiersma, A. Zbinden…·M. Polymenidou
This study shows TDP-43 oligomerization and RNA binding work together to control its stability and localization, and their loss leads to different pathological outcomes.
DOI 10.1101/2022.05.23.493029