In-silico screening of drug candidates for thermoresponsive liposome formulations
M. Balouch, M. Srejber, M. Soltys, P. Janska, F. Stepanek, K. Berka
This paper develops an in silico model to predict API permeability across lipid bilayers and validates it using fluorescent dyes, then applies it to screen DrugBank for suitable drug candidates for thermoresponsive liposomes.
bioRxiv · May 11, 2020Pharmacology & Toxicology