Combined strategy of siRNA and osteoclast actin cytoskeleton automated imaging to identify novel regulators of bone resorption shows a non-mitotic function for anillin.
J. Maurin, A. Morel, C. Hassen-Khodja, V. Vives, P. Jurdic, I. Machuca-Gayet, A. Blangy
The paper identifies novel regulators of osteoclast cytoskeleton and shows Anillin has a non-mitotic role in bone resorption by controlling RhoA levels.
bioRxiv · Oct 4, 2018Cell Biology