Cancer BiologybioRxiv
Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of malignant pleural mesotheliomas to CDK4/6 inhibition
S. Paternot, E. Raspe, C. Meiller…·P. P. Roger
This study shows that CDK4 phosphorylation predicts sensitivity of malignant pleural mesothelioma to CDK4/6 inhibitors, with 80% of tumors expressing phosphorylated CDK4.
DOI 10.1002/1878-0261.13351