An ortholog of P. falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion
L. B. Thornton, P. Teehan, K. Floyd, C. Cochrane, A. Bergmann, B. Riegel, P. Roepe, Z. Dou
This study identifies TgCRT as a key regulator of the endolysosomal system in Toxoplasma gondii, showing its role in maintaining VAC integrity and facilitating parasite invasion.
bioRxiv · Oct 4, 2018Microbiology