KSTITCH links cellular morphology and gene expression in spatial transcriptomics
Shashwat Kumar, Yingxiao Shi, Tuulia Vallius, Chi‐Ping Day, P.-A. Absil, Anuj Srivastava, Sridhar S. Hannenhalli, Vishaka Datta
STITCH pairs size-independent tangent-PCA contour shape modes with expression factors by canonical correlation, recovering keratinocyte, fibroblast and melanoma shape-expression links in Xenium and CosMx data.
bioRxiv · Aug 26, 2026 · PreprintBioinformatics✦ In-depth digest