Optimized data representation and convolutional neural network model for predicting tumor purity
Gerald J. Sun, David F. Jenkins, Pablo E. Cingolani, Jonathan R. Dry, Zhongwu Lai
Deep Purity (DePuty) uses convolutional neural networks to predict tumor purity from SNP-based copy number and minor allele frequency data without matched normals, outperforming existing methods with fewer samples.
bioRxiv · Oct 17, 2019 · PreprintBioinformatics