Phenotypic screening converges on CDK9 inhibition as a therapeutic strategy in translocation renal cell carcinoma
Dharma R. Thapa, Riva Deodhar, Adam P. Skepner, Prathyusha Konda, Meng Zhou, Joseph P. Bluck, C. Pichlo, Yantong Cui, Paige Stocker, Prateek Khanna, Jiao Li, Jonathan M. Tsai, Alison Leed, Sandy Gould, Maria Alimova, , Srinivas Raghavan Viswanathan
The paper identifies CDK9 inhibition as a therapeutic strategy for translocation renal cell carcinoma through phenotypic screening and mechanistic analysis.
bioRxiv · Aug 25, 2025 · PreprintCancer Biology