Author

Pascale Walters

BC Cancer Agency

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrew McPhersoniD· 3 shared Daniel LaiiD· 3 shared Samuel A. J. R. AparicioiD· 3 shared Sohrab P. ShahiD· 3 shared Adi SteifiD· 2 shared Beixi WangiD· 2 shared Christian SteidliD· 2 shared Ciara H. O’FlanaganiD· 2 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Andrew McPhersonORCID

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3 papers

Recent·Most cited

clonealign: statistical integration of independent single-cell RNA & DNA-seq from human cancers

Kieran R. Campbell, Adi Steif, Emma Laks, Hans Zahn, Daniel Lai, Andrew McPherson, Hossein Farahani, Farhia Kabeer, Ciara H. O’Flanagan, Justina Biele, Jazmine Brimhall, Beixi Wang, Pascale Walters, Alexandre Bouchard‐Côté, Samuel A. J. R. Aparicio, Sohrab P. Shah

clonealign integrates single-cell RNA and DNA sequencing data from cancer samples to identify clone-specific gene expression patterns and dysregulated pathways.

Genome biology · Mar 12, 2019Peer-reviewedBioinformatics

Probabilistic cell type assignment of single-cell transcriptomic data reveals spatiotemporal microenvironment dynamics in human cancers

Allen W. Zhang, Ciara H. O’Flanagan, Elizabeth A. Chavez, Jamie L. Lim, Andrew McPherson, Matt Wiens, Pascale Walters, Tim Chan, Brittany Hewitson, Daniel Lai, Anja Mottok, Clémentine Sarkozy, Lauren C. Chong, Tomohiro Aoki, Xuehai Wang, , Sohrab P. Shah

CellAssign probabilistically assigns cell types to scRNA-seq data, revealing spatiotemporal dynamics in human cancers like ovarian and follicular lymphoma.

bioRxiv · Jan 16, 2019 · PreprintBioinformatics

Resource: Scalable whole genome sequencing of 40,000 single cells identifies stochastic aneuploidies, genome replication states and clonal repertoires

Emma Laks, Hans Zahn, Daniel Lai, Andrew McPherson, Adi Steif, Jazmine Brimhall, Justina Biele, Beixi Wang, Tehmina Masud, Diljot S. Grewal, Cydney B Nielsen, Samantha Leung, Viktoria Bojilova, Maia A. Smith, Oleg Golovko, , Samuel A. J. R. Aparicio

bioRxiv · Sep 13, 2018 · PreprintGenomics