The genetic, clinical and immune landscape of clonal hematopoiesis across adulthood in the multi-ancestry Mount Sinai Million cohort
Myvizhi Esai Selvan, Namira Ashraf, Rujula Pradeep, Leyla Giordano, Max L. Dougherty, Paul Chevelev, Carl Jannes Neuse, Daniel I. Nathan, Bridget Kelly Marcellino, Robert J. Klein, Zeynep Hulya Gumus
This study characterizes clonal hematopoiesis across adulthood and genetic ancestry in a large cohort, finding age-related increases in prevalence, ancestry-specific differences, and associations with immune markers and disease outcomes.
medRxiv · Oct 26, 2026 · PreprintGenetic & Genomic Medicine