Systematic benchmarking of low-input whole exome sequencing workflows for longitudinal ctDNA profiling in pancreatic ductal adenocarcinoma
L C James, Graeme J. Thorn, Cecilia H Morel, PCRFTB, Hemant Mahendrakumar Kocher, Helen Ross‐Adams, Claude Chelala
This study benchmarks three low-input whole exome sequencing workflows for ctDNA profiling in PDAC, showing Agilent V8 provides best performance in low-input settings.
bioRxiv · Jul 3, 2026 · PreprintGenomics