EGFL7 promotes immune evasion in glioblastoma by interaction with integrin β2
Sukrit Mahajan, Philipp Abe, Fanny Ehret, Carina Fabian, Nora Heinig, Marc Gentzel, Rajinder Gupta, Julieta Aprea, Paul Warnke, Eirini Moysoglou, Beatrice Wasser, Stephan Grabbe, Andreas Dahl, Kathrin Barth, Marc Schmitz, , Mirko H. H. Schmidt
This study identifies EGFL7 as a driver of immune evasion in glioblastoma by interacting with integrin β2, showing that targeting this axis enhances immunotherapy efficacy.
bioRxiv · Jul 28, 2025 · PreprintCancer Biology