Author

Pio Passariello

Rutgers, The State University of New Jersey

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

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David Render· 1 shared Dylan Jay· 1 shared Madhav Subramaniyam· 1 shared Márió Szegedy· 1 shared Yash SharmaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBioinformatics

David Render

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 23, 2026

Averaging in gene perturbation benchmarks hides perturbation-strength variation: Consequences for model evaluation

Yash Sharma, Madhav Subramaniyam, Pio Passariello…·Márió Szegedy

The paper evaluates how averaging perturbation responses in gene perturbation benchmarks affects the ability to assess perturbation-strength variation, finding that current models fail to reliably recover perturbation identity.

DOI 10.64898/2026.10.20.760537

humanCRISPR screen