Motif V acts as a Regulator of Energy Transduction Between the Flavivirus NS3 ATPase and RNA Binding Cleft
K. E. DuPont, R. Davidson, M. McCullagh, B. J. Geiss
This study investigates the role of Motif V in NS3 helicase energy transduction, finding that mutations increase dsRNA unwinding rates and alter structural communication between ATP and RNA binding sites.
bioRxiv · Nov 14, 2019Biochemistry