Author

R. de Wit

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

M. S. van der Heijden· 3 shared N. Mehra· 3 shared A. A. M. van der Veldt· 2 shared H. J. G. van de Werken· 2 shared H. M. Westgeest· 2 shared J. A. Nakauma-Gonzalez· 2 shared J. L. Boormans· 2 shared J. van Riet· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

M. S. van der Heijden

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Author profile →

3 papers

Recent·Most cited

T Cell-to-Stroma Enrichment (TSE) score: a gene expression metric that predicts response to immune checkpoint inhibitors in patients with urothelial cancer

M. M. Rijnders, J. A. Nakauma-Gonzalez, D. G. J. Robbrecht, A. Gil-Jimenez, H. E. Balcioglu, A. A. M. Oostvogels, M. J. B. Aarts, J. L. Boormans, P. Hamberg, M. S. van der Heijden, B. E. Szabados, G. J. L. H. van Leenders, N. Mehra, J. Voortman, H. M. Westgeest, , M. P. Lolkema

bioRxiv · May 30, 2022 · PreprintCancer Biology

Molecular characterization reveals genomic and transcriptomic subtypes of metastatic urothelial carcinoma

J. A. Nakauma-Gonzalez, M. Rijnders, J. van Riet, M. S. van der Heijden, J. Voortman, E. P. J. G. Cuppen, N. Mehra, S. van Wilpe, S. F. Oosting, L. L. Rijstenberg, H. M. Westgeest, E. Zwarthoff, R. de Wit, A. A. M. van der Veldt, H. J. G. van de Werken, , J. L. Boormans

This paper identifies genomic and transcriptomic subtypes of metastatic urothelial carcinoma using multi-omics analysis, revealing potential therapeutic targets and patient-specific strategies.

bioRxiv · Mar 17, 2021Cancer Biology

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

L. F. van Dessel, J. van Riet, M. Smits, Y. Zhu, P. Hamberg, M. S. van der Heijden, A. M. Bergman, I. M. van Oort, R. de Wit, E. E. Voest, N. Steeghs, T. N. Yamaguchi, J. Livingstone, P. C. Boutros, J. W. M. Martens, , M. P. Lolkema

This study uses whole-genome sequencing to identify four distinct genotypes in metastatic castration-resistant prostate cancers, with potential clinical implications for patient stratification.

bioRxiv · Oct 7, 2019Cancer Biology

R. de Wit · henhao