The hunt for ancient prions: Archaeal prion-like domains form amyloids and substitute for yeast prion domains
T. Zajkowski, M. D. Lee, S. S. Mondal, A. Carbajal, R. Dec, P. D. Brennock, R. W. Piast, J. E. Snyder, N. B. Bense, W. Dzwolak, D. F. Jarosz, L. J. Rothschild
This paper identifies prion-like domains in Archaea that form amyloids and transmit non-Mendelian inheritance, suggesting prions existed in the last universal common ancestor.
bioRxiv · Jul 20, 2020 · PreprintEvolutionary Biology