Genomic drivers of large B-cell lymphoma resistance to CD19 CAR-T therapy
M. D. Jain, B. Ziccheddu, C. A. Coughlin, R. Faramand, A. J. Griswold, K. M. Reid, O. Landgren, F. L. Locke, F. Maura, M. L. Davila, J. H. Schatz
This study identifies genomic factors associated with resistance to CD19 CAR-T therapy in large B-cell lymphoma by analyzing whole genome sequencing data from treated patients.
bioRxiv · Aug 25, 2021 · PreprintCancer Biology