Author

R. J. Sims

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Bommi-Reddy· 1 shared A. Conery· 1 shared A. Hingway· 1 shared D. N. Mayhew· 1 shared E. Terzo· 1 shared J. E. Wilson· 1 shared M. J. Steinbaugh· 1 shared S. Park-Chouinard· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

A. Bommi-Reddy

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1 paper

Recent·Most cited

Cancer BiologybioRxivDec 26, 2021

CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enhancers to inhibit the proliferation of ER+ breast cancer cells

A. Conery, A. Bommi-Reddy, S. Park-Chouinard…·R. J. Sims

This study shows that inhibiting CREBBP/EP300 acetyltransferase suppresses ER+ breast cancer growth by disrupting FOXA1-bound enhancers, offering a new therapeutic strategy.

DOI 10.1371/journal.pone.0262378

humanbulk RNA-seq