Combination therapy of metformin with sodium selenite reverses effects of monotherapy on nitric oxide production, IL-1β and TNF-α release, and upregulates relative expression of Bcl-2 by LPS-activated human primary monocytes in T-cell acute lymphoblastic leukemia
F. Rostane, N. Sari, I. Bali, R. Messali, Z. Hadjidj, M. Miliani, I. Belhassena, C. El Mezouar, M. Aribi
This study shows that combining metformin and sodium selenite reduces NO, IL-1β, and TNF-α release while increasing Bcl-2 expression in T-ALL monocytes.
bioRxiv · Jan 4, 2022 · PreprintImmunology