LIR-dependent LMX1A/LMX1B autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience
J. D. Lane, N. Jimenez-Moreno, P. Stathakos, Z. Anton, D. Shoemark, R. Sessions, R. Witzgall, M. Caldwell
This study shows LMX1A and LMX1B regulate autophagy in human midbrain dopaminergic neurons through LIR interactions, affecting mitochondrial function and resilience to rotenone toxicity.
bioRxiv · May 14, 2019 · PreprintCell Biology