Interactions in CSF1-driven Tenosynovial Giant Cell Tumors
D. G. P. van IJzendoorn, M. Matusiak, G. W. Charville, G. Spierenburg, S. Varma, D. R. C. Colburg, M. A. J. van de Sande, K. van Langevelde, D. G. Mohler, K. N. Ganjoo, N. Q. Bui, R. S. Avedian, J. V. M. G. Bovee, R. Steffner, R. B. West, M. van de Rijn
The paper identifies GFPT2 as a marker for synoviocytes in TGCT and shows neoplastic cells lack CSF1R, suggesting current therapies may not target them effectively.
bioRxiv · Jun 1, 2022Cancer Biology