Author

Ramon Bonte

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

George J. G. RuijteriD· 2 shared Henk J. BlomiD· 2 shared Marcel J. T. ReindersiD· 2 shared Michiel BongaertsiD· 2 shared Serwet DemirdasiD· 2 shared Ans van der Ploeg· 1 shared Edwin H. Jacobs· 1 shared Esmée OussoreniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

George J. G. RuijterORCID

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2 papers

Recent·Most cited

Prioritizing disease-causing metabolic genes by integrating metabolomics with whole exome sequencing data

Michiel Bongaerts, Ramon Bonte, Serwet Demirdas, Hidde H. Huidekoper, Janneke G. Langendonk, Martina Wilke, Walter G. de Valk, Henk J. Blom, Marcel J. T. Reinders, George J. G. Ruijter

This paper introduces Reafect, a computational method that integrates metabolomics and whole exome sequencing to prioritize disease-causing genes in inborn errors of metabolism, showing improved accuracy in identifying causative variants.

Molecular Genetics and Metabolism · May 25, 2022Peer-reviewedGenetic & Genomic Medicine

Screening for inborn errors of metabolism using untargeted metabolomics and out-of-batch controls

Michiel Bongaerts, Ramon Bonte, Serwet Demirdas, Edwin H. Jacobs, Esmée Oussoren, Ans van der Ploeg, Margreet A. E. M. Wagenmakers, Robert M.W. Hofstra, Henk J. Blom, Marcel J. T. Reinders, George J. G. Ruijter

The paper develops a normalization method for untargeted metabolomics data to reduce batch effects and improve detection of metabolic biomarkers using out-of-batch controls.

Metabolites · Dec 25, 2020Peer-reviewedBioinformatics