Author

Randa Melhem

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:imaging· 1

Frequent Co-Authors

Haochang ShouiD· 2 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Andrew A. CheniD· 1 shared Andrew Chen· 1 shared Christos A. DavatzikosiD· 1 shared Elizabeth A. HorwathiD· 1 shared Fengling HuiD· 1 shared Jessica McClintockiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Haochang ShouORCID

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2 papers

Recent·Most cited

Imputation-Based Harmonization Mitigates Site Effects Without Data Leakage in Machine Learning Studies

Noah Hillman, Andrew Chen, Fengling Hu, Simon Vandekar, Randa Melhem, Lori L. Beason‐Held, Theodore Satterthwaite, Christos A. Davatzikos, Haochang Shou, Russell T. Shinohara, Alzheimer’s Disease Neuroimaging Initiative

The paper introduces MIRTH, an imputation-based harmonization method that mitigates site effects in neuroimaging data without data leakage, achieving high predictive accuracy in machine learning studies.

bioRxiv · Oct 5, 2026 · PreprintNeuroscience

ComBatFamQC: Streamlining Interactive Batch-Effect Diagnostics and Harmonization for Neuroimaging Data in R

Zheng Ren, Elizabeth A. Horwath, Siyan Wen, Randa Melhem, Jessica McClintock, William Evan Johnson, Russell Taki Shinohara, Andrew A. Chen, Haochang Shou

ComBatFamQC provides an R package for batch-effect diagnosis and harmonization in neuroimaging data, integrating visualization, statistical tests, and harmonization methods.

bioRxiv · Aug 4, 2026 · PreprintBioinformatics