Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes
Samuel K. Powell, Will Liao, Callan P. O’Shea, Sarah Kammourh, Sadaf Ghorbani, Raymond Rigat, Rahat Elahi, PJ Michael Deans, Derek J. Le, Poonam Agarwal, Wei Qiang Seow, Ke Wang, Schahram Akbarian, Kristen Brennand
The paper maps 3D chromatin structures in neuronal subtypes and shows how schizophrenia risk loci reorganize during differentiation, linking regulatory loops to gene function.
bioRxiv · Jul 17, 2023 · PreprintGenomics