Cancer BiologyCell Reports MethodsPeer-reviewed
Biobank of genetically defined murine prostate cancer tumoroids uncovers oncogenic pathways and drug vulnerabilities driven by PTEN-loss
Jessica Kalla, Thomas Dillinger, Zlata Pavlovicova…·Gerda Egger
This study establishes a murine tumoroid biobank to identify oncogenic pathways and drug vulnerabilities in prostate cancer, finding that PTEN loss drives cancer pathways and that specific compounds inhibit tumor growth.
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