The Structural Basis of Genome Silencing: The Inactive X Chromosome Resolved by Electron Spectroscopic Imaging
Zahra Baghestani, Helena Alvarenga, Ren Li, Matthew McNeil, Eden Fussner, Mike Strauss
This study uses Electron Spectroscopic Imaging to resolve the structural organization of the inactive X chromosome, revealing chromatin, RNA, and protein features in 3D.
bioRxiv · Oct 30, 2026 · PreprintCell Biology