Potentiation of EGFR mutant lung cancer treatment targeting replication stress.
Reshma Bhowmick, John J. Turchi, Shadia Ibrahim Jalal
This paper shows that combining osimertinib with NERx-329, a replication stress inhibitor, enhances cell death in EGFR-mutant lung cancer cells and reduces resistance.
bioRxiv · Apr 18, 2025 · PreprintCancer Biology