Time-course Transcriptomics Reveals the Impact of Treponema pallidum on Microvascular Endothelial Cell Function and Phenotype
Sean Waugh, Mara C. Goodyear, Alloysius Gomez, Akash Ranasinghe, Karen Lithgow, Reza Falsafi, Robert E. W. Hancock, Amy Huei‐Yi Lee, Caroline E. Cameron
This study uses time-course transcriptomics to show how Treponema pallidum alters endothelial cell pathways, leading to endothelial-to-mesenchymal transition and potential disease mechanisms.
Frontiers in Microbiology · Oct 6, 2025Peer-reviewedMolecular Biology