Non-parametric mixture models identify trajectories of childhood immune development relevant to asthma and allergy
Howard H.F. Tang, Shu Mei Teo, Danielle C. M. Belgrave, Michael D. Evans, Daniel J. Jackson, Marta Brożyńska, Merci M.H. Kusel, Sebastian Lennox Johnston, James E. Gern, Robert F. Lemanske, Angela Simpson, Adnan Čustović, Peter David Sly, Patrick G. Holt, Kathryn E. Holt, Michael Inouye
The paper identifies three distinct immune development trajectories in childhood using unsupervised clustering, revealing a high-risk atopic cluster associated with allergic diseases.
bioRxiv · Dec 20, 2017 · PreprintSystems Biology