Author

Robert P Brown

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Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Ascia Eskin· 1 shared Bogdan Pasaniuc· 1 shared Bruno ReversadeiD· 1 shared Gleb KichaeviD· 1 shared Hane LeeiD· 1 shared Kirk E Lohmueller· 1 shared Stanley F Nelson· 1 shared

Activity by Year

2015-2015 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Ascia Eskin

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1 paper

Recent·Most cited

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders

Robert P Brown, Hane Lee, Ascia Eskin, Gleb Kichaev, Kirk E Lohmueller, Bruno Reversade, Stanley F Nelson, Bogdan Pasaniuc

This paper improves causal variant identification in exome sequencing for monogenic disorders by incorporating ancestry information to reduce false negatives and improve variant filtering.

European Journal of Human Genetics · Apr 22, 2015Peer-reviewedGenetics