MSstatsResponse: Semi-parametric statistical model enhances detection of drug-protein interactions in chemoproteomics experiments
Sarah Szvetecz, Devon Kohler, Joel D. Federspiel, S. Denise Field, Pierre Jean-Beltran, Robert Seward, Hyunsuk Suh, Liang Xue, Olga Vitek A
MSstatsResponse improves detection of drug-protein interactions in chemoproteomics by using a semi-parametric statistical model that avoids fixed curve shapes, enhancing accuracy and robustness in low-replicate and low-dose settings.
Molecular & Cellular Proteomics · Aug 12, 2026Peer-reviewedBioinformatics