Impact of Realistic 3D Tumor Microarchitecture on Cellular Dosimetry and Radiobiological Response in Targeted Radionuclide Therapy
Treshan Ayesh Peirispulle, Robert Ware, Steven Korevaar, Prabath Hetti Mudiyanselage, John Thangarajah, Ruwan Tennakoon
This study shows that realistic 3D tumor models improve dose distribution and radiobiological predictions in radionuclide therapy compared to simplified spherical models.
bioRxiv · Sep 24, 2026 · PreprintCancer Biology