Metabolic engineering of a tyrosine-specific phenylpropanoid pathway in plants
Caroline Van Beirs, Max Bentelspacher, Congwei Xie, Celien Van de Velde, Sandrien Desmet, Robin De Wulf, Wout Boerjan, Jaime Barros-Rios, Bartel Vanholme
The paper engineers a tyrosine-specific phenylpropanoid pathway in plants and finds that it can overcome a seedling-lethal phenotype but causes developmental defects due to auxin transport inhibitor accumulation.
bioRxiv · Dec 16, 2025 · PreprintPlant Biology