Ultrasensitive detection of TCR hypervariable region in solid-tissue RNA-seq data
Bo Li, Taiwen Li, Binbin Wang, Ruoxu Dou, Jean-Chrisophe Pignon, Toni K Choueiri, Sabina Signoretti, Jun S Liu, Xiaole Shirley Liu
TRUST detects TCR CDR3 regions in solid-tissue RNA-seq data with high sensitivity, even at low sequencing depth, and is applicable to large tumor cohorts.
bioRxiv · Sep 9, 2016Bioinformatics