Author

Ryan J. Hansen

Boundless Bio (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anthony B. PinkertoniD· 1 shared Auzon Steffy· 1 shared Christian A. HassigiD· 1 shared Christina N. CurtisiD· 1 shared Edison TseiD· 1 shared Ellis J. CurtisiD· 1 shared Georgi K. MarinoviD· 1 shared Guiping WangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anthony B. PinkertonORCID

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1 paper

Recent·Most cited

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

Jun Tang, Natasha E. Weiser, Guiping Wang, Sudhir Chowdhry, Ellis J. Curtis, Yanding Zhao, Ivy Tsz-Lo Wong, Georgi K. Marinov, Rui Li, Philip Hanoian, Edison Tse, Salvador Garcia Mojica, Ryan J. Hansen, Joshua Plum, Auzon Steffy, , Howard Y. Chang

This paper identifies transcription-replication conflict as a vulnerability in ecDNA-containing cancers and demonstrates that CHK1 inhibition selectively kills these tumors.

Nature · Nov 6, 2024Peer-reviewedCancer Biology