Selection of DNA aptamers targeting PirAB toxin for potential biosensing applications in acute hepatopancreatic necrosis disease (AHPND)
Vanessa Aguilar-Sánchez, Rylee McKay, Alejandra Hernández‐Santoyo, Sonia A. Soto-Rodríguez, Jonathan Perreault
This paper optimizes SELEX to develop DNA aptamers targeting PirAB toxin for early detection of AHPND, achieving Kd values of 65-700 nM for PirB and 1-3 µM for PirAB complex.
bioRxiv · Oct 16, 2026 · PreprintMolecular Biology