STAT5-dependent regulation of CDC25A by miR-16 controls proliferation and differentiation in FLT3-ITD acute myeloid leukemia
G. Sueur, A. Boutet, M. Gotanegre, V. De Mas, A. Besson, S. Manenti, S. Bertoli
This study identifies a FLT3-ITD/STAT5/miR-16/CDC25A axis that regulates proliferation and differentiation in FLT3-ITD AML by controlling CDC25A levels through miR-16.
bioRxiv · Jul 19, 2019Cancer Biology