Combined EGFR and ROCK inhibition in TNBC leads to cell death via impaired autophagic flux
S. Rontogianni, S. Iskit, S. van Doorn, D. S. Peeper, M. Altelaar
This study shows that combined EGFR and ROCK inhibition in TNBC causes cell death by blocking autophagic flux, leading to autophagic vacuole accumulation.
bioRxiv · Jun 5, 2019Cancer Biology