Particulate matter constituents trigger the formation of extracellular amyloid beta and Tau-containing plaques and neurite shortening in vitro
A. Sebastijanovic, L. M. A. Camassa, V. Malmborg, S. Kralj, J. Pagels, U. Vogel, S. Zienolddiny-Narui, I. Urbancic, T. Koklic, J. Strancar
This study shows that particulate matter exposure in vitro causes amyloid beta plaques and neurite shortening in neuron-like cells, resembling Alzheimer's disease features.
bioRxiv · Mar 27, 2024 · PreprintPharmacology & Toxicology