Author

S. Leighow

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Evolutionary Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

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B. Zhao· 1 shared C. Liu· 1 shared H. Inam· 1 shared J. R. Pritchard· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperEvolutionary Biology

B. Zhao

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1 paper

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Multi-scale predictions of drug resistance epidemiology suggest a new design principle for rational drug design.

S. Leighow, C. Liu, H. Inam, B. Zhao, J. R. Pritchard

This paper identifies a new principle in drug resistance where the most likely mutations, not the most resistant ones, dominate clinical outcomes, suggesting a strategy to minimize resistance through drug design.

bioRxiv · Sep 19, 2019 · PreprintEvolutionary Biology