Host range expansion of Shigella phage Sf6 evolves through the dual roles of its tailspike
S. Subramanian, J. A. Dover, K. N. Parent, S. M. Doore
This paper shows that phage Sf6 evolves to expand its host range by mutating its tailspike protein to overcome inhibitory LPS interactions with serotype 2a2.
bioRxiv · Apr 6, 2022 · PreprintMicrobiology