Mitochondrial COA7 is a heme-binding protein involved in the early stages of complex IV assembly.
L. E. Formosa, S. Maghool, A. J. Sharpe, B. Reljic, L. Muellner-Wong, D. A. Stroud, M. Ryan, M. J. Maher
This study identifies COA7 as a heme-binding protein essential for complex IV assembly, revealing its structure and heme-binding mechanism in mitochondrial biogenesis.
bioRxiv · Jun 10, 2021 · PreprintBiochemistry