Cone-shaped HIV-1 capsids are transported through intact nuclear pores
V. Zila, E. Margiotta, B. Turonova, T. G. Müller, C. E. Zimmerli, S. Mattei, M. Allegretti, K. Börner, J. Rada, B. Müller, M. Lusic, H.-G. Kräusslich, M. Beck
The paper shows HIV-1 capsids can enter the nucleus intact through nuclear pores, challenging the idea that uncoating must occur before nuclear import.
bioRxiv · Jul 30, 2020Microbiology