Repurposing of Miglustat to inhibit the coronavirus Severe Acquired Respiratory Syndrome SARS-CoV-2
S. Rajasekharan, R. Milan Bonotto, Y. Kazungu, L. Nascimento Alves, M. Poggianella, P. Martinez Orellana, N. Skoko, S. Polez, A. Marcello
This study shows that Miglustat inhibits SARS-CoV-2 by targeting glucosidases, reducing viral proteins and infectious virus release at clinically achievable concentrations.
bioRxiv · May 18, 2020 · PreprintMicrobiology