Cheminformatics identification of phenolics as modulators of penicillin binding protein (PBP) 2x of Streptococcus pneumoniae towards interventive antibacterial therapy
J. O. Aribisala, N. W. Sthebe, S. Sabiu
This study identifies phenolics, particularly silicristin, as potential modulators of PBP2x in S. pneumoniae with strong binding affinity, suggesting their use in antibacterial therapy.
bioRxiv · Oct 2, 2023 · PreprintMicrobiology