Computing the inducibility of B cell lineages under a context-dependent model of affinity maturation: Applications to sequential vaccine design
J. Mathews, E. Van Itallie, K. Wiehe, S. Schmidler
The paper develops a computational model to estimate the inducibility of specific antibodies during vaccine design by simulating context-dependent mutation rates in B cell lineages.
bioRxiv · Oct 13, 2023Immunology