S. Tal

Activity-dependent COX-2 proteolysis generates a catalytically inactive fragment that affects aerobic respiration and proliferation

The paper shows that COX-2 proteolysis generates catalytically inactive fragments that affect mitochondrial function and cell proliferation in colon tumors.

CRISPR Spacers Acquired from Plasmids Primarily Target Backbone Genes, Making Them Valuable for Predicting Potential Hosts and Host Range

This study predicts plasmid hosts and host ranges using CRISPR spacers, finding they primarily target plasmid backbone genes and reveal horizontal gene transfer networks.