BUB1 regulates non-homologous end joining pathway to mediate radioresistance in triple-negative breast cancer
S. Sriramulu, S. Thoidingjam, W.-M. Chen, O. Hassan, F. Siddiqui, S. L. Brown, B. Movsas, M. D. Green, A. J. Davis, C. Speers, E. Walker, S. Nyati
This study identifies BUB1 as a regulator of non-homologous end joining (NHEJ) in triple-negative breast cancer (TNBC), showing that its inhibition sensitizes TNBC cells to radiotherapy.
bioRxiv · May 7, 2024Cancer Biology