S. Thore

Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin

The paper determines the structure of CPSF73-CPSF100 heterodimer and its interaction with Symplekin, revealing conserved architecture and key binding regions.

Leigh Syndrome-inducing Mutations Affect LRPPRC / SLIRP Complex Formation

This study identifies the region of LRPPRC critical for SLIRP interaction and shows how LSFC mutations disrupt complex formation.

In vitro dimerization of human RIO2 kinase

The paper reports three atomic structures of human RIO2 kinase showing it forms a homodimer, which locks it in an inactive apo state and may serve as a nuclear import signal.