Cell BiologybioRxivPreprint
Inactivation of the Niemann Pick C1 cholesterol transporter 1 (NPC1) restricts SARS-CoV-2 infection
P. La Rosa, J. Tiberi, E. Palermo…·M. T. Fiorenza
This study shows that inactivating NPC1 reduces SARS-CoV-2 infection by trapping ACE2 in lysosomes and disrupting viral entry.
DOI 10.1101/2023.12.13.571570